Lieber (1979) published a collection of many studies purporting to show a reliable lunar influence on various areas of human behaviour, although Rotton and Kelly (1985), using meta-analysis, have fiercely contested this claim. However whereas studies of social behaviour can be easily criticized for neglecting a variety of contributing variables, biochemical studies, like those of Rounds (1975), who has found a lunar periodicity in the concentration of neurotransmitter-like substances from human blood, are more difficult to refute.